When can controlled substances classified as CIIs be refilled?

Controlled substances classified as CII, or Schedule II substances, are subject to stringent regulations due to their potential for abuse and dependency. By law, these substances cannot be refilled, which means that a new prescription must be issued each time a patient requires medication. This restriction is in place to ensure careful monitoring of how these potent drugs are prescribed and dispensed, minimizing the risk of misuse.

Understanding this is crucial for a pharmacy professional, as it impacts how prescriptions are managed and dispensed. It highlights the importance of communication between the patient and the healthcare provider, as obtaining a new prescription emphasizes the need for ongoing evaluation of the patient's treatment and medication needs. Hence, the correct answer is that CII controlled substances can never be refilled under existing regulations.