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Conducting an audit of controlled substances classified as Schedule C drugs on a monthly basis is an essential practice for pharmacies to ensure compliance with regulatory requirements and to maintain proper inventory control. This regular auditing helps to identify discrepancies or potential diversion of these substances in a timely manner.

The monthly frequency allows pharmacies to monitor the usage and stock levels effectively, making it easier to detect any irregularities that could indicate misuse or theft. It aligns with best practices in pharmacy management and regulatory compliance, as it provides a systematic approach to safeguarding controlled substances.

In contrast, less frequent audits might result in missed opportunities to catch discrepancies, while more frequent audits could lead to unnecessary administrative burdens on pharmacy staff. Therefore, a monthly audit strikes a balance between oversight and operational efficiency, making it the most suitable option for ensuring the integrity and security of controlled substances within the pharmacy setting.